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THE

The Science

Peer-Reviewed Research

The science behind
Biotite.

Every ingredient in our formula is supported by published, peer-reviewed research. Below are the clinical studies and scientific publications that inform our formulations—so you can see exactly why each ingredient earns its place.

01
Astaxanthin
Keto-carotenoid Antioxidant
1
Protective effects of astaxanthin on skin: Recent scientific evidence, possible mechanisms, and potential indications
Singh KN, Patil S, Barkate H.
J Cosmet Dermatol. 2020 Jan;19(1):22–27 PMID: 31141292 PubMed
2
Effects of Astaxanthin Supplementation on Skin Health: A Systematic Review of Clinical Studies
Ng QX, De Deyn MLZQ, Loke W, Foo NX, Chan HW, Yeo WS.
J Diet Suppl. 2021;18(2):169–182 PMID: 32202443 PubMed
02
Bakuchiol
Natural Retinol Alternative
3
Natural Retinol Analogs Potentiate the Effects of Retinal on Aged and Photodamaged Skin: Results from In Vitro to Clinical Studies
Brown A, Furmanczyk M, Ramos D, Ribes A, Pons L, Bustos J, de Henestrosa ARF, Granger C, Jourdan E.
Dermatol Ther (Heidelb). 2023 Oct;13(10):2299–2317 PMID: 37615835 PubMed
4
Applications of bakuchiol in dermatology: Systematic review of the literature
Puyana C, Chandan N, Tsoukas M.
J Cosmet Dermatol. 2022 Dec;21(12):6636–6643 PMID: 36176207 PubMed
03
Blue Tansy Oil
Tanacetum annuum
5
Chemical Characterization and Antifungal Activity of Blue Tansy (Tanacetum annuum) Essential Oil and Crude Extracts against Fusarium oxysporum
Ettakifi H, Abbassi K, Maouni S, Erbiai EH, Rahmouni A, Legssyer M, Saidi R, Lamrani Z, Esteves da Silva JCG, Pinto E, Maouni A.
Antibiotics (Basel). 2023 Sep 16;12(9):1451 PMID: 37760747 PubMed
04
Jojoba Oil
Simmondsia chinensis
6
Jojoba Oil: An Updated Comprehensive Review on Chemistry, Pharmaceutical Uses, and Toxicity
Gad HA, Roberts A, Hamzi SH, Gad HA, Touiss I, Altyar AE, Kensara OA, Ashour ML.
Polymers (Basel). 2021 May 24;13(11):1711 PMID: 34073772 PubMed
7
Jojoba in dermatology: a succinct review
Pazyar N, Yaghoobi R, Ghassemi MR, Kazerouni A, Rafeie E, Jamshydian N.
G Ital Dermatol Venereol. 2013 Dec;148(6):687–691 PMID: 24442052 PubMed
05
Lavender Essential Oil
Lavandula angustifolia
8
Anti-psoriatic effect of Lavandula angustifolia essential oil and its major components linalool and linalyl acetate
Rai VK, Sinha P, Yadav KS, Shukla A, Saxena A, Bawankule DU, Tandon S, Khan F, Chanotiya CS, Yadav NP.
J Ethnopharmacol. 2020 Oct 28;261:113127 PMID: 32623016 PubMed
9
The Effects of Lavender Essential Oil and its Clinical Implications in Dentistry: A Review
Kajjari S, Joshi RS, Hugar SM, Gokhale N, Meharwade P, Uppin C.
Int J Clin Pediatr Dent. 2022 May–Jun;15(3):385–388 PMID: 35991803 PubMed
06
Rosehip Oil
Rosa canina seed oil
10
Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils
Lin TK, Zhong L, Santiago JL.
Int J Mol Sci. 2017 Dec 27;19(1):70 PMID: 29280987 PubMed
11
Therapeutic Applications of Rose Hips from Different Rosa Species
Mármol I, Sánchez-de-Diego C, Jiménez-Moreno N, Ancín-Azpilicueta C, Rodríguez-Yoldi MJ.
Int J Mol Sci. 2017 May 25;18(6):1137 PMID: 28587101 PubMed
07
Rosemary Essential Oil
Rosmarinus officinalis
12
Development and Evaluation of an Antimicrobial Formulation Containing Rosmarinus officinalis
Macedo LM, Santos ÉMD, Ataide JA, Silva GTSE, Guarnieri JPO, Lancellotti M, Jozala AF, Rosa PCP, Mazzola PG.
Molecules. 2022 Aug 9;27(16):5049 PMID: 36014289 PubMed
08
Sea Buckthorn Oil
Hippophae rhamnoides
13
Abundance of active ingredients in sea-buckthorn oil
Zielińska A, Nowak I.
Lipids Health Dis. 2017 May 19;16(1):95 PMID: 28526097 PubMed
14
Sea Buckthorn (Hippophaë rhamnoides L.) Oil Improves Atopic Dermatitis-Like Skin Lesions via Inhibition of NF-κB and STAT1 Activation
Hou DD, Di ZH, Qi RQ, Wang HX, Zheng S, Hong YX, Guo H, Chen HD, Gao XH.
Skin Pharmacol Physiol. 2017;30(5):268–276 PMID: 28873377 PubMed
15
The Effect of Sea Buckthorn (Hippophae rhamnoides L.) Seed Oil on UV-Induced Changes in Lipid Metabolism of Human Skin Cells
Gęgotek A, Jastrząb A, Jarocka-Karpowicz I, Muszyńska M, Skrzydlewska E.
Antioxidants (Basel). 2018 Aug 23;7(9):110 PMID: 30142919 PubMed

All publications listed are peer-reviewed and sourced from PubMed / NCBI. Citations are provided for educational purposes to highlight the scientific evidence supporting our ingredient choices. These studies do not constitute medical advice, and Biotite Skin products are not intended to diagnose, treat, cure, or prevent any disease.

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